Guide to Patagonia's Monsters & Mysterious beings

I have written a book on this intriguing subject which has just been published.
In this blog I will post excerpts and other interesting texts on this fascinating subject.

Austin Whittall

Thursday, December 26, 2013

Diabetes Neanderthals and modern Latinos

A paper published in Nature on Christmas titled: Sequence variants in SLC16A11 are a common risk factor for type 2 diabetes in Mexico puts forth the idea that Latin Americans share a genetic risk factor picked up from Neanderthals, which is not very common outisde of the American continent and which makes them more prone to diabetes:

Below is the keyline:

The risk haplotype carries four amino acid substitutions, all in SLC16A11; it is present at ~50% frequency in Native American samples and ~10% in east Asian, but is rare in European and African samples. Analysis of an archaic genome sequence indicated that the risk haplotype introgressed into modern humans via admixture with Neanderthals.

Once again a genetic marker linking Amerindians to Neanderthals but, unsurprisingly skipping their alleged East Asian "ancestors" who hardly share any of these key markers with American Indians. It is clear that current East Asians are not the stock that led to the peopling of America.

The paper explains why Latinos are almost twice as likely to develop Type 2 diabetes as Caucasians and African-Americans

I am working on a long article on these gentetic links and differences which I hope to post soon.

My previous post on Neanderthals and Amerindians

Patagonian Monsters - Cryptozoology, Myths & legends in Patagonia Copyright 2009-2013 by Austin Whittall © 

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