tag:blogger.com,1999:blog-8137409915847697670.post8914653944723046967..comments2024-03-17T18:41:00.382-03:00Comments on Patagonian monsters: Heterozygosity for dummiesAWhttp://www.blogger.com/profile/11389280995003336103noreply@blogger.comBlogger4125tag:blogger.com,1999:blog-8137409915847697670.post-60830220566611826482016-11-29T20:10:01.073-03:002016-11-29T20:10:01.073-03:00"This leads me to ask, what if African hetero..."This leads me to ask, what if African heterozygosity was enriched by recent admixture with other hominins in Africa? an inflow of different relic alleles elevated African diversity above that of non-Africans. Could current lower Amerindian heterozygosity reflect an ancient population just like that of Denisovans or Neanderthals?"<br /><br />Agree on everything. I've made exactly the same points in several posts on http://anthropogenesis.kinshipstudies.org/. Notably, while we see ancient, divergent and African-specific uniparental markers (Y-DNA A00 and A, mtDNA L0, L1, L2, L4, L5) in African-Americans (a well-attested slave migration from West Africa in recent times), we don't see them anywhere along the putative out-of-Africa route(s) presumably used by humans 50,000 years ago. They are not found in the Sahul, West Eurasia or East Asia. Provided the phylogenies are correct, they must have introgressed in into modern Africans from archaic hominins in Africa.German Dziebelhttps://www.blogger.com/profile/10703679732205862495noreply@blogger.comtag:blogger.com,1999:blog-8137409915847697670.post-73558431373792058162016-11-14T09:47:46.160-03:002016-11-14T09:47:46.160-03:00 I appreciate your honest reply. Indeed, what you... I appreciate your honest reply. Indeed, what you are divulging is very relevant, not easy to gather from other sources/papers and is well documented,…and necessarily implies a certain amount of knowledge in the matter. Some subjects are within the very limits of which is known,… certainly, it is impossible to advance in their study without making speculations...which may lead (via further research and development) to interesting, and up to now, unthinkable implications. So… go on with them.<br />Thanks for your attention<br />Marcelo<br />Marcelo Bruyerenoreply@blogger.comtag:blogger.com,1999:blog-8137409915847697670.post-77057532618378665692016-11-13T15:47:21.409-03:002016-11-13T15:47:21.409-03:00Thanks Marcelo for your comment.
Don't think t...Thanks Marcelo for your comment.<br />Don't think that my knowledge on this matter is greater than yours, I am a total rookie in this!.<br />I too have wondered how did they survive considering that they were so "inbred" (http://phys.org/news/2016-06-inbred-neanderthals-left-humans-genetic.html), so I will look into this, because it seems there is an incongruence here..AWhttps://www.blogger.com/profile/11389280995003336103noreply@blogger.comtag:blogger.com,1999:blog-8137409915847697670.post-28126065477839036722016-11-11T20:48:08.919-03:002016-11-11T20:48:08.919-03:00Hello Austin
In this essay you explain, among man...Hello Austin<br /> In this essay you explain, among many other things, that the genetic diversity is a function of 2 factors, heterozigosity and number of alleles,…and that a rich one has a positive role in the surviveability of a specie.<br />Your approach to the subject is, as usual, very lucid and particularly clarifier…but my knowledge in the matter is limited, so mine are not comments… just questions to try to better understand.<br />Given the fact that Neanderthal populations had the lowest heterozigosity, ¿How can be explained that they managed to survive along 150/200 Kya or so, in Eurasia, sometimes in very adverse environments?...<br />Could the other factor involved, the allele richness (if known), have been, in contrast, somewhat high, in order to maintain a reasonably rich genetic diversity?....<br />My modest and schematic reasoning is the following, ¿Didn´t they need this last, to became into the dominant specie, during most of this period?...<br />If not, ¿Up to what degree can we correlate genetic diversity with, what seems to me, an apparently “successful “ population?<br />Sorry for too many questions… I may be wrong in more than one concept… but I know of no other site than can put light into this subject.<br />Thank in advance for your reply<br />Best regards<br />Marcelo<br />Marcelo Bruyerenoreply@blogger.com